Darko Antwi was born in Ashanti New Town, Kumasi, in May 1976 to Kwaku Antwi and Elizabeth Donkor. After his secondary education at Bekwai Seventh Day Adventist, he taught in local kindergarten and primary schools for five years. In September 2002 he traveled to the United Kingdom.
While in England, Antwi has been occupied by a string of odd jobs, including the position of a factory labourer, fabric launderer and newspaper columnist.
He is currently the proprietor of Seaweed Books, organizers of Ahenkro Book Fair and Miss Akoto Book Club. His latest project is Cocoa, Gold and Metaphor, an anthology of contemporary Ghanaian poets.